First case report: adolescent thoraco-lumbar scoliosis patient over 45° who reached the end of treatment. On the left, from left to right, in the first and then in the third line: all x-rays of this case report of a patient that reached the end of treatment (each x-ray is marked with the corresponding date). On the left, midline: graph with the results obtained, dates and Risser test. On the right, in top-down direction: the brace used, and the posterior and sagittal aesthetic appearance at the end of treatment. A.A. has been evaluated the first time in December 2004, presenting with a second x-ray showing a thoraco-lumbar left scoliosis progressed in 18 months from 44° (Risser 0) to 61° (Risser 2). Fusion had been proposed, but refused. She started treatment with the Sforzesco brace 23 hours per day and SEAS exercises 3 times a week (45'): after 5 months she was 49° (Risser 3). Treatment continued other 6 months 23 hours per day, then 22 per 6 months, and brace was continously and gradually weaned 2 hours every 6 months: she improved after 3 years of treatment (41°, Risser 4) and 4 years (38°, Risser 4). At the last x-ray after 48 hours without the brace, and 5 years and 6 months of continuos Sforzesco brace treatment and SEAS exercises, she finished treatment at 39°.