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Table 1 Research gaps and future research directions for the surgical management of scoliosis

From: The surgical management of scoliosis: a scoping review of the literature

Research gaps Future research directions
There are few focused systematic reviews relative to the extensive scoliosis literature, reflecting a lack of emphasis on knowledge synthesis and knowledge translation. Knowledge synthesis: Perform a series of high-quality focused systematic reviews examining important clinical questions.
There is a striking paucity of randomized controlled trials (RCTs), and the existing RCTs are characterized by generally small sample sizes. Knowledge translation: Use existing systematic reviews to inform a series of evidence-based decision aids and preliminary clinical practice guidelines.
Very few high-level studies have investigated surgical indications, surgical approaches, surgical techniques, or implant selection. Future RCTs: Conduct a series of surveys or planning meetings to engage clinicians, patients, methodologists, and other knowledge users in the design and conduct of future large RCTs.
Patient important outcomes such as function, health-related quality of life, pain, and rates or re-operation have been infrequently reported in comparison to radiological outcomes and rates of complications. Ongoing scoping work: Clarify inconsistent outcome reporting and identifying practical strategies for methodological improvement.