Table 2 Comparisons on the clotting capabilities, haemoglobin change, blood products transfused, and total blood loss in patients with or without using TXA
From: Use of Tranexamic Acid (TXA) on reducing blood loss during scoliosis surgery in Chinese adolescents
Surgical parameters | Tranexamic acid | P | |
|---|---|---|---|
|  | TXA (N = 55) | Control (N = 35) |  |
Clotting capability | Â | Â | Â |
 Pre-op PT | 11.56 ± 0.87 | 11.32 ± 1.04 | 0.24 |
 Pre-op INR | 1.07 ± 0.07 | 1.05 ± 0.06 | 0.18 |
 Pre-op APTT | 37.24 ± 3.88 | 37.92 ± 4.83 | 0.46 |
Haemoglobin change | Â | Â | Â |
 Latest postop – preop | −2.99 ± 1.58 | −3.33 ± 1.56 | 0.33 |
Equivalent volume of whole blood/packed red blood cell transfused | Â | Â | Â |
 Intra-operative | 472.50 ± 370.48 | 891.67 ± 358.35 | 0.04 |
 Post-operative | 150.00 ± 256.04 | 333.33 ± 516.40 | 0.45 |
Volume of cell saver blood transfused back to patient (ml) | 575.36 ± 412.25 | 1684.26 ± 1233.91 | <0.01 |
Volume of platelet transfused (ml) | 194.41 ± 125.19 | 219.28 ± 144.17 | 0.59 |
Volume of fresh frozen plasma (FFP) transfused (ml) | 798.86 ± 520.00 | 863.18 ± 458.48 | 0.67 |
Latest post-operative hemoglobin level | 10.00 ± 1.18 | 9.66 ± 0.75 | 0.34 |
Number of days for hemoglobin level reaching stable level post-operatively | 4.39 ± 2.12 | 4.23 ± 1.69 | 0.80 |
Total blood loss by anesthetist estimation (ml) | 1826.11 ± 1081.45 | 3889.60 ± 2440.80 | <0.01 |
Total blood loss per segment (ml/segment) | 135.62 ± 78.10 | 328.44 ± 222.68 | <0.01 |