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Table 3 Sensitivity analysis on different linear regression models on the use of tranexamic acid, infusion of coagulation factors, and clotting capability on the total blood loss controlled for confounding factors

From: Use of Tranexamic Acid (TXA) on reducing blood loss during scoliosis surgery in Chinese adolescents

Models TXA Age at surgery Number of segments fused Max major curve Bone graft Length of surgery Total FFP transfused Total platelet transfused PT (pre-op) INR (pre-op) APTT (pre-op) r2 Β P
1       0.31 −4.98 <0.01
2      0.45 −5.25 <0.01
3       0.44 −5.25 0.05
4     0.27 −3.99 0.14
5    0.32 −5.26 <0.01
6   0.46 −5.25 <0.01
7   0.48 −4.93 0.10
8 0.39 −4.01 0.15
  1. TXA, use of tranexamic acid (Yes/No), FFP fresh frozen plasma, PT prothrombin time, INR international normalised ratio, APTT activated partial thromboplastin time