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Table 3 Sensitivity analysis on different linear regression models on the use of tranexamic acid, infusion of coagulation factors, and clotting capability on the total blood loss controlled for confounding factors

From: Use of Tranexamic Acid (TXA) on reducing blood loss during scoliosis surgery in Chinese adolescents

Models

TXA

Age at surgery

Number of segments fused

Max major curve

Bone graft

Length of surgery

Total FFP transfused

Total platelet transfused

PT (pre-op)

INR (pre-op)

APTT (pre-op)

r2

Î’

P

1

✓

✓

✓

✓

✓

✓

     

0.31

−4.98

<0.01

2

✓

✓

✓

✓

✓

✓

✓

    

0.45

−5.25

<0.01

3

✓

✓

✓

✓

✓

✓

 

✓

   

0.44

−5.25

0.05

4

✓

✓

✓

✓

✓

✓

✓

✓

   

0.27

−3.99

0.14

5

✓

✓

✓

✓

✓

✓

  

✓

✓

✓

0.32

−5.26

<0.01

6

✓

✓

✓

✓

✓

✓

✓

 

✓

✓

✓

0.46

−5.25

<0.01

7

✓

✓

✓

✓

✓

✓

 

✓

✓

✓

✓

0.48

−4.93

0.10

8

✓

✓

✓

✓

✓

✓

✓

✓

✓

✓

✓

0.39

−4.01

0.15

  1. TXA, use of tranexamic acid (Yes/No), FFP fresh frozen plasma, PT prothrombin time, INR international normalised ratio, APTT activated partial thromboplastin time