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Table 5 Sensitivity of differentiating known clinical groups

From: Psychometric validation of the EuroQoL 5-Dimension 5-Level (EQ-5D-5L) in Chinese patients with adolescent idiopathic scoliosis

  Treatment (observation versus bracing or surgery)   Treatment (observation versus bracing)  
  Observation (n = 139) Bracing/Surgery (n = 88)     Observation (n = 139) Bracing (n = 67)    
  Mean SD Mean SD P-value* ESa   Mean SD Mean SD P-value* ESa  
EQ-5D-5L 0.96 0.07 0.89 0.15 <0.001 0.66 EQ-5D-5L 0.96 0.07 0.89 0.14 <0.001 0.62  
SRS-22r        SRS-22r        
Function/activity 4.93 0.20 4.53 0.55 <0.001 0.95 Function/activity 4.93 0.20 4.58 0.50 <0.001 0.92  
Pain 4.79 0.29 4.48 0.56 <0.001 0.70 Pain 4.79 0.29 4.52 0.49 <0.001 0.66  
Appearance 4.03 0.55 3.78 0.74 0.004 0.39 Appearance 4.03 0.55 3.68 0.68 <0.001 0.57  
Mental Health 4.49 0.51 4.31 0.67 0.028 0.29 Mental Health 4.49 0.51 4.32 0.63 0.038 0.30  
Satisfaction with management 0.25 1.02 2.37 2.01 <0.001 −1.33 Satisfaction with management 0.25 1.02 2.13 2.01 <0.001 −1.18  
Total 4.56 0.28 4.25 0.52 <0.001 0.73 Total 4.56 0.28 4.25 0.48 <0.001 0.78  
  Treatment (Bracing versus Surgery)   Duration of Bracing  
  Bracing (n = 67) Surgery (n = 21)     <1 year (n = 34) ≥1 year (n = 20)    
  Mean SD Mean SD P-value* ESa   Mean SD Mean SD P-value* ESa  
EQ-5D-5L 0.89 0.14 0.86 0.18 0.372 0.21 EQ-5D-5L 0.82 0.15 0.91 0.14 0.023 −0.66  
SRS-22r        SRS-22r        
Function/activity 4.58 0.50 4.38 0.69 0.156 0.33 Function/activity 4.40 0.52 4.58 0.51 0.226 −0.34  
Pain 4.52 0.49 4.33 0.73 0.184 0.30 Pain 4.54 0.34 4.48 0.58 0.657 0.14  
Appearance 3.68 0.68 4.11 0.83 0.021 −0.56 Appearance 3.60 0.74 3.67 0.62 0.732 −0.10  
Mental Health 4.32 0.63 4.30 0.83 0.924 0.02 Mental Health 4.27 0.65 4.28 0.66 0.972 −0.01  
Satisfaction with management 2.13 2.01 3.15 1.84 0.046 −0.53 Satisfaction with management 2.43 2.12 2.52 1.96 0.875 −0.04  
Total 4.25 0.48 4.25 0.67 0.991 0.002 Total 4.19 0.49 4.22 0.50 0.780 −0.08  
  Cobb angle (mild or moderate versus severe)   Modified Lenke Classification  
  ≤40° (n = 205) >40° (n = 20)     Thoracic curve (n = 86) Lumbar curve (n = 38) Thoracic & Lumbar curve (n = 103)  
  Mean SD Mean SD P-value* ESa   Mean SD Mean SD Mean SD P-value*
EQ-5D-5L 0.93 0.11 0.91 0.12 0.402 0.19 EQ-5D-5L 0.92 0.13 0.93 0.11 0.95 0.10 0.271
SRS-22r        SRS-22r        
Function/activity 4.78 0.41 4.69 0.52 0.349 0.20 Function/activity 4.73 0.44 4.81 0.39 4.79 0.42 0.522
Pain 4.68 0.43 4.55 0.53 0.216 0.27 Pain 4.64 0.39 4.69 0.38 4.68 0.50 0.753
Appearance 3.96 0.63 3.72 0.76 0.116 0.34 Appearance 3.94 0.70 3.84 0.58 3.97 0.61 0.583
Mental Health 4.45 0.55 4.16 0.81 0.037 0.41 Mental Health 4.41 0.62 4.36 0.61 4.45 0.55 0.703
Satisfaction with management 1.09 1.84 0.90 1.47 0.662 0.11 Satisfaction with management 1.10 1.86 0.99 1.82 1.07 1.77 0.949
Total 4.46 0.40 4.25 0.57 0.032 0.42 Total 4.42 0.45 4.42 0.37 4.46 0.41 0.788
  1. * P-value of independent t-test or analysis of variance test, where appropriate
  2. aCohen’s effect size was calculated as the difference between mean scores, divided by pooled SD
  3. N number of subjects, SD standard deviation, ES effect size