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Table 5 Sensitivity of differentiating known clinical groups

From: Psychometric validation of the EuroQoL 5-Dimension 5-Level (EQ-5D-5L) in Chinese patients with adolescent idiopathic scoliosis

 

Treatment (observation versus bracing or surgery)

 

Treatment (observation versus bracing)

 
 

Observation (n = 139)

Bracing/Surgery (n = 88)

   

Observation (n = 139)

Bracing (n = 67)

   
 

Mean

SD

Mean

SD

P-value*

ESa

 

Mean

SD

Mean

SD

P-value*

ESa

 

EQ-5D-5L

0.96

0.07

0.89

0.15

<0.001

0.66

EQ-5D-5L

0.96

0.07

0.89

0.14

<0.001

0.62

 

SRS-22r

      

SRS-22r

       

Function/activity

4.93

0.20

4.53

0.55

<0.001

0.95

Function/activity

4.93

0.20

4.58

0.50

<0.001

0.92

 

Pain

4.79

0.29

4.48

0.56

<0.001

0.70

Pain

4.79

0.29

4.52

0.49

<0.001

0.66

 

Appearance

4.03

0.55

3.78

0.74

0.004

0.39

Appearance

4.03

0.55

3.68

0.68

<0.001

0.57

 

Mental Health

4.49

0.51

4.31

0.67

0.028

0.29

Mental Health

4.49

0.51

4.32

0.63

0.038

0.30

 

Satisfaction with management

0.25

1.02

2.37

2.01

<0.001

−1.33

Satisfaction with management

0.25

1.02

2.13

2.01

<0.001

−1.18

 

Total

4.56

0.28

4.25

0.52

<0.001

0.73

Total

4.56

0.28

4.25

0.48

<0.001

0.78

 
 

Treatment (Bracing versus Surgery)

 

Duration of Bracing

 
 

Bracing (n = 67)

Surgery (n = 21)

   

<1 year (n = 34)

≥1 year (n = 20)

   
 

Mean

SD

Mean

SD

P-value*

ESa

 

Mean

SD

Mean

SD

P-value*

ESa

 

EQ-5D-5L

0.89

0.14

0.86

0.18

0.372

0.21

EQ-5D-5L

0.82

0.15

0.91

0.14

0.023

−0.66

 

SRS-22r

      

SRS-22r

       

Function/activity

4.58

0.50

4.38

0.69

0.156

0.33

Function/activity

4.40

0.52

4.58

0.51

0.226

−0.34

 

Pain

4.52

0.49

4.33

0.73

0.184

0.30

Pain

4.54

0.34

4.48

0.58

0.657

0.14

 

Appearance

3.68

0.68

4.11

0.83

0.021

−0.56

Appearance

3.60

0.74

3.67

0.62

0.732

−0.10

 

Mental Health

4.32

0.63

4.30

0.83

0.924

0.02

Mental Health

4.27

0.65

4.28

0.66

0.972

−0.01

 

Satisfaction with management

2.13

2.01

3.15

1.84

0.046

−0.53

Satisfaction with management

2.43

2.12

2.52

1.96

0.875

−0.04

 

Total

4.25

0.48

4.25

0.67

0.991

0.002

Total

4.19

0.49

4.22

0.50

0.780

−0.08

 
 

Cobb angle (mild or moderate versus severe)

 

Modified Lenke Classification

 
 

≤40° (n = 205)

>40° (n = 20)

   

Thoracic curve (n = 86)

Lumbar curve (n = 38)

Thoracic & Lumbar curve (n = 103)

 
 

Mean

SD

Mean

SD

P-value*

ESa

 

Mean

SD

Mean

SD

Mean

SD

P-value*

EQ-5D-5L

0.93

0.11

0.91

0.12

0.402

0.19

EQ-5D-5L

0.92

0.13

0.93

0.11

0.95

0.10

0.271

SRS-22r

      

SRS-22r

       

Function/activity

4.78

0.41

4.69

0.52

0.349

0.20

Function/activity

4.73

0.44

4.81

0.39

4.79

0.42

0.522

Pain

4.68

0.43

4.55

0.53

0.216

0.27

Pain

4.64

0.39

4.69

0.38

4.68

0.50

0.753

Appearance

3.96

0.63

3.72

0.76

0.116

0.34

Appearance

3.94

0.70

3.84

0.58

3.97

0.61

0.583

Mental Health

4.45

0.55

4.16

0.81

0.037

0.41

Mental Health

4.41

0.62

4.36

0.61

4.45

0.55

0.703

Satisfaction with management

1.09

1.84

0.90

1.47

0.662

0.11

Satisfaction with management

1.10

1.86

0.99

1.82

1.07

1.77

0.949

Total

4.46

0.40

4.25

0.57

0.032

0.42

Total

4.42

0.45

4.42

0.37

4.46

0.41

0.788

  1. * P-value of independent t-test or analysis of variance test, where appropriate
  2. aCohen’s effect size was calculated as the difference between mean scores, divided by pooled SD
  3. N number of subjects, SD standard deviation, ES effect size
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Scoliosis and Spinal Disorders

ISSN: 2397-1789

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