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Table 1 Strength of evidence grading used in these guidelines. Questions on effectiveness (treatment results) and diagnosis (assessment) have been considered

From: 2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth

Strength of evidence Question Meaning
I Effectiveness Multiple Randomized Controlled Trials or Systematic Reviews of such studies
Diagnosis Multiple Randomized Controlled Trials, or Cross-sectional Studies with verification by reference (gold) standard, or Systematic Reviews of such studies
II Effectiveness One Randomized Controlled Trial
Diagnosis One Randomized Controlled Trial, or one Cross-sectional Study with verification by reference (gold) standard
III Effectiveness Multiple Controlled nonrandomized Studies or Systematic Reviews of such studies
Diagnosis Multiple Cross-sectional Studies with incomplete & unbalanced verification with reference (gold) standard
IV Effectiveness Other studies
Diagnosis
V Effectiveness SOSORT consensus with more than 90% of agreement
Diagnosis
VI Effectiveness SOSORT consensus with 70 to 89% of agreement
Diagnosis