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Table 1 Research into Possible Cause and Effect in Spinal Deformity

From: The transformation of spinal curvature into spinal deformity: pathological processes and implications for treatment

1967. IS: An investigation of genetic and environmental factors. J Bone Jt Surg 49-A: 1005

1974. The early onset of osteoarthritis in juvenile and AIS. J Bone Jt Surg 56: 1575

1979. Equilibrium factors as predictors of the prognosis in AIS. Clin Orthop and Related Res 152: 232

1980. Analysis of lateral predominance in AIS with special reference to curve convexity. Spine 5: 512.

1981. Proprioceptive function in children in AIS. Spine 6: 560

1988. Growth and ethnicity in scoliosis. Acta Orthop Scand 59: 310

1988. Growth hormone profiles in pubertal girls with AIS. Spine 13: 139

1988. Idiopathic scoliosis: clinical, morphometric, histopathological correlation. J Pediatric Orth 8:147

1988. Muscle spindles in the paraspinal musculature of patients with AIS. Spine 13: 461

1989. Equilibrial dysfunction in scoliosis–cause or effect? J Spinal Disord 2: 184

1989. Psychological implications of genetic factors in scoliosis. Loss, Grief are 3: 169

1989. Spinal mobility in AIS and normal controls. Spine 14: 757

1990. Zinc status in patients with IS. Spine 15: 65

1991. A theory concerning prenatal origins of cerebral lateralization in humans. Psych Review 98: 299

1991. Hereditary orthodontic anomalies and IS. Int Orthop 15: 57

1991. Idiopathic scoliosis and asymmetry of form and function. Spine 16: 84

1991. MRI imaging of the brain stem in AIS. Spine 16: 761

1993. AIS and joint laxity: a study with somatosensory evoked potentials. Spine 18: 918

1993. AIS: early menarche, normal growth. Spine 18: 529–535

1993. Complex balance reactions in different sensory conditions: Adolescents +/- IS. J Orthop Res 11: 215

1994. The potential role of the elastic fiber system in AIS. J Bone Jt Surg 76-A: 1193

1995. Decreased incidence of scoliosis in hearing impaired children. Spine 20: 776

1995. Increased femoral neck shaft angles in AIS. Spine 20: 303

1996. Melatonin, possible role in pathogenesis of AIS. Spine 21: 1147

1997. Abdominal reflexes. J Pediatric Orthop 17: 105

1997. Incidence and risk factors for mitral valve prolapse in severe AIS. Pediatric Cardiol 18: 425

1997. Osteopenia in AIS: A primary problem or secondary to the spinal deformity? Spine 22: 1716

1998. Neural axis abnormalities in infantile and juvenile patients with spinal deformity. Spine 23: 206

1999. A genomic approach to scoliosis pathogenesis. Lupus 8:356

1999. Familial back shape in AIS. Acta Orthop Scand 62: 131

1999. MRI evaluation of multifidus muscles in AIS. Pediatr Radiol 29: 360

1999. Preoperative, postoperative pathologic changes for paravertebral muscles in IS. J China Med 28: 131

1999. Spinal cord insults in the prenatal, perinatal, and neonatal periods. Dev Med Child Neurol 41: 311

2000. Generalized low areal and volumetric bone mineral density in AIS. J Bone Min Res 15: 1587

2000. IS: Relation between the vertebral canal and the vertebral bodies. Spine 25: 1360

2001. Evolution of scoliosis in six children treated with growth hormone. J Ped Orthop 10: 197

2001. Influences of different types of progressive IS on static and dynamic postural control. Spine 26: 1052

2001. The pathogenesis of IS: uncoupled neuro-osseous growth? Eur Spine J 10: 473

2001. Visual deficiency and scoliosis. Spine 26: 48

2002. A genetic locus for AIS linked to chromosome 19p13.3. Am J Hum Genet 71: 401

2002. Assignment of a locus for autosomal dominant IS to human chromosome 17p11. Hum Genet 111:401

2002. Association between estrogen receptor gene polymorphisms and curve severity of IS. Spine 27: 2357

2002. Cellularity of human annulus tissue. Histopathology 41: 531

2002. Premature termination mutations in FBN1. Am J Hum Genet 223

2003. Allelic variants of human melatonin 1A receptor in patients with familial AIS. Spine 28: 2025

2003. Cold-induced sweating syndrome is caused by mutations in CRLF1 gene. Am J Hum Gen 72: 375

2003. IS as a presenting sign of familial neurologic abnormalities. Spine 28: 40

2005. Abnormal peri-pubertal anthropometric measurements and growth pattern in AIS. Spine 28: 2152