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Figure 1 | Scoliosis

Figure 1

From: Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy

Figure 1

Double neuro-osseous theory for the pathogenesis of AIS in girls. Disharmony in spine and trunk between the two nervous systems, autonomic (leptin-hypothalamic-sympathetic nervous system - LHS - concept) and somatic (escalator concept). The drawing of the girl shows three extraspinal sites where left-right skeletal length asymmetries have been detected in AIS subjects - ribs [30, 31], upper arms [32] and iliac height [33, 34]; the latter two asymmetries correlate significantly with adjacent spinal curve severity suggesting the presence of vertebral growth plate asymmetries [32, 34–36]. Asymmetries are also found in tibial lengths [34, 37], femoral anteversion [38, 39], femoro-tibial correlations [40, 41] but not tibial torsion [39, 42]. There is some evidence suggesting a "primary" vertebral growth plate disorder in AIS [43, 44] but this is controversial [45].

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Scoliosis and Spinal Disorders

ISSN: 2397-1789

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