Volume 9 Supplement 1

11th International Conference on Conservative Management of Spinal Deformities - SOSORT 2014 Annual Meeting

Open Access

Is it worthwhile to measure bone quality in patients with adolescent idiopathic scoliosis?

  • Xuan Zhou1,
  • Qing Du1,
  • Jianan Li2,
  • Xiaohua He3,
  • Li Zhao4 and
  • Peijie Chen5
Scoliosis20149(Suppl 1):O14

https://doi.org/10.1186/1748-7161-9-S1-O14

Published: 4 December 2014

Keywords

Idiopathic scoliosisBone strengthQuantitative ultrasoundFemale adolescentsMenstruationRisser’s sign.

Background

The application of quantitative ultrasound measurement in the studies of AIS is still sparse.

Aim

The aims of this study were to compare bone quality (speed-of-sound, SOS and z-scores) between female adolescent idiopathic scoliosis (AIS) patients and controls using quantitative ultrasound examination, and further to analyze the relationship between bone strength and maturation, severity and type of scoliosis in AIS patients measured by the same technique along the long axis of the distal radius.

Design

Case series.

Methods

88 female AIS patients and 58 healthy female controls from 10 to 16 years of age were included. Quantitative ultrasound measurements were performed at the left distal end of the radius, and the standard method to estimate speed of sound was recorded. Z-score was then calculated. Comparisons were made between the values of SOS and z-score values in patients and age-matched controls.

Results

The SOS values of 88 female AIS patients were significantly lower than age-matched adolescent controls (P<0.01). However, there was no statistical correlations between bone density and types of scoliosis, as well as family history (p>0.05). The SOS values among different severity groups of curvature were found to be significant, particularly between 10 to 20 degrees and 20 to 40 degree groups, but there was no significant correlation between SOS and Cobb angles. Statistically significant correlations were also found between pre- and post-menarche status. There was significant difference in the SOS values in different Risser stages (p <0.05), and more skeletally immature patients were more osteopenic.

Conclusions

Comparing to non-scoliotic controls, female AIS patients have generally lower bone quality measuring by quantitative ultrasound. Slower maturation may be one of the factors that affect the bone quality in these patients. Different types of scoliosis and family history have no effect on the bone quality in these patients. Although there were significant differences between SOS values and Cobb angles, this may be due to slower bone maturation than the severity of the AIS curve. It is recommended that quantitative ultrasound measurement should be undertaken in AIS patients.

Authors’ Affiliations

(1)
Department of Rehabilitation of Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
(2)
Rehabilitation Department of Jiangsu Province Hospital
(3)
Palmer College of Chiropractic
(4)
Department of Pediatric Orthopedics of Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
(5)
Department of Kinesiology of Shanghai University of Sport

Copyright

© Zhou et al; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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