Table 2 Summary of study designs, methodologies, and outcome of high-intensity zones (HIZs) in the lumbar spine
From: The association of high-intensity zones on MRI and low back pain: a systematic review
Author | Year | Sample size (N) | Mean age (years) | Radiologic methods (MRI) | Prevalence | The highest prevalence at disc level | Association with LBP |
|---|---|---|---|---|---|---|---|
Carragee et al. | 2000 | 96 | 38 | N/A | No | ||
Symptomatic, 42 Asymptomatic, 54 | Symptomatic, 36 Asymptomatic, 40 | 1.5T anterior and posterior T2-weighted | Symptomatic, 25 (59%) Asymptomatic, 85 (24%) | ||||
Hancock et al. | 2012 | 60 | 37 | N/A | No | ||
Symptomatic, 30 Control, 30 | 1.5T sagittal T1 and T2-weighted axial T2-weighted | Symptomatic, 18 (30%) Control, 7 (22%) | |||||
Takatalo et al. | 2012 | 554 | N/A | No | |||
Symptomatic, 387 Asymptomatic, 167 | 21 | 1.5T sagittal and axial T2-weighted | Symptomatic, 13 (3.2%) Asymptomatic, 4 (2%) | ||||
Wang et al. | 2012 | 623 | L4/5 | Yes | |||
Symptomatic, 317 Asymptomatic, 306 | 50 | 1.5T sagittal T1-weighted sagittal and axial T2-weighted | Symptomatic, 115 (36%) Asymptomatic, 85 (28%) | ||||
Liu et al. | 2014 | 151 | 43 | L4/5 | Yes | ||
Symptomatic, 72 Asymptomatic, 79 | Symptomatic, 44 Asymptomatic, 43 | 1.5T sagittal T1 and T2-weighted | Symptomatic, 33 (45.8%) Asymptomatic, 16 (20%) | ||||
Yang et al. | 2015 | 57 | 29 | N/A | Yes | ||
Symptomatic, 25 Asymptomatic, 32 | Symptomatic, 30 Asymptomatic, 28 | 3.0T sagittal and axial T1- and T2-weighted | Symptomatic, 17 (61%) Asymptomatic, 11 (32%) |